대한수면의학회

Objectives: This research was performed in order to observe the neuropsychological implication and functional anatomical source of event related potentials(ERP) by studying of correlations between event related potentials and neuropsychological tests. Methods: The latency and voltage of P100 of visual evoked potential (VEP), and N120 and P300 of event related potentials were studied in 56 patients and their correlations with neuropsychological tests were computed. Results: The tests showing significant correlation with latency P100 were visual continous performance test(VCPT) and contingent continous performance test(CCPT) without any significant correlation with voltage of P100. In latency of N120 category test and verbal IQ of KWIS showed significant correlation, and in voltage of N120, finger tapping test, VCPT, CCPT and digit symbol test displayed significant correlations. The latency of P300 had significant correlation with trail making A test and Stroop test. In the voltage of P300 significant correlations were shown with trail making B test, digit symbol test and Wechsler memory scale, finger tapping test, stroop test, VCPT and CCPT. Conclusion : N120 may be considered to reflect the function of medial frontal lobe and P300 may be considered to be developed from the subcortical connection of medial temporal lobe, hippocampus, thalamus, basal ganglia and medial frontal lobe.

Neuropsychological tests;Event related potential;P100;N120;P300;Functional neuroanatomy;