수면정신생리

수면정신생리 (18권1호 23-28)

Prevalence and Clinical Features of Probable REM Sleep Behavior Disorder-An Epidemiological Study in Osan City

유력 렘수면 행동장애 환자 유병률과 임상 양상-오산시 역학 연구

Choe, Young-Min;Yoon, In-Young;Kim, Ki-Woong;Lee, Sang-Don;Ju, Ga-Won;Park, Joon-Hyuk;

Department of Neuropsychiatry, Seoul National University College of Medicine, Seoul National University Bundang Hospital;Department of Neuropsychiatry, Seoul National University College of Medicine, Seoul National University Bundang Hospital;Department of Neuropsychiatry, Seoul National University College of Medicine, Seoul National University Bundang Hospital;Department of Neuropsychiatry, Seoul National University College of Medicine, Seoul National University Bundang Hospital;Department of Neuropsychiatry, Seoul National University College of Medicine, Seoul National University Bundang Hospital;Department of Neuropsychiatry, Jeju National University Hospital;

DOI : http://dx.doi.org/10.14401/KASMED.2011.18.1.023

Abstract

Objectives: REM sleep behavior disorder (RBD) has received little attention in epidemiologic studies. This study aimed to determine the prevalence of probable REM sleep behavior disorder (pRBD) in the elderly population and its clinical features. Methods: A random sample of 1,588 was selected from a roster of 14,050 elderly population living in Osan city. The subjects were asked to fill out the REM sleep behavior disorder screening questionnaire (RBDSQ). Subjects whose score were 5 or higher on RBDSQ underwent a diagnostic phase of person-to-person assessment by experts in RBD. Results: Among 1,588 subjects, 886 elderly subjects participated in the screening phase and 123 subjects were assessed in the diagnostic phase. Eleven subjects were diagnosed as having pRBD, so prevalence was 1.5% (95% CI=0.70-2.30%). The frequency of depression and cognitive decline was significantly increased in patients with pRBD compared to subjects without pRBD, and there was no difference in sleep disturbances between two groups. Conclusions: Probable REM sleep behavior disorder is not rare in the elderly but frequently under-recognized. More attention should be paid to evaluation and treatment of RBD.

Keywords

REM sleep behavior disorder;REM sleep behavior disorder screening questionnaire;Prevalence;Elderly;